Stability Indicating LC-Method for Estimation of Paracetamol and Lornoxicam in Combined Dosage Form
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چکیده
منابع مشابه
Stability Indicating LC-Method for Estimation of Paracetamol and Lornoxicam in Combined Dosage Form
A simple, specific and stability indicating reversed phase high performance liquid chromatographic method was developed for the simultaneous determination of paracetamol and lornoxicam in tablet dosage form. A Brownlee C-18, 5 μm column having 250×4.6 mm i.d. in isocratic mode, with mobile phase containing 0.05 M potassium dihydrogen phosphate:methanol (40:60, v/v) was used. The flow rate was 1...
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A simple, sensitive and precise stability indicating HPLC method has been developed for the estimation of rabeprazole and itopride in combined dosage form. A Phenomenex Gemini C-18, 5 μm column with a mobile phase containing 0.02 M ammonium acetate (pH 6): acetonitrile: methanol (45: 20: 35, v/v/v) was used. The flow rate was 1.0 mL min and effluents were monitored at 284 nm. Rabeprazole and it...
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INTRODUCTION Lornoxicam (LORN) a nonsteroidal antiinflammatory drug of oxicam class is marketed in combination with Paracetamol, a common analgesic for acute inflammatory disease of joints. MATERIALS AND METHODS LORN and Paracetamol (PCM) were estimated at 280 nm by densitometry using silica gel 60 F254 as stationary phase and a premix of toluene: chloroform: methanol: formic acid (3:5:1.5:0....
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A simple, rapid and precise method was developed for the quantitative estimation of prasugrel hydrochloride in pharmaceutical dosage form. A chromatographic separation of prasugrel and its degradants was achieved with Zorbax XDB C(8), 150 × 4.6 mm, 3.5μm analytical column using aqueous solution of 0.05 M ammonium acetate pH 4.5 with acetic acid-acetonitrile (40:60 v/v). The instrumental setting...
متن کاملStability-indicating UFLC method for uncoupling and estimation of impurities in clopidogrel, aspirin and omeprazole in their tablet dosage form using PDA detection
In this paper a fast and novel stability-indicating ultra fast LC method for separation and estimation of impurities in clopidogrel and aspirin in their combined tablet dosage form and omeprazole was developed. The separation of USP related substances of clopidogrel (A, B and C), aspirin (D), omeprazole (A, B and C) and few other unknown impurities was detected by using ultra fast liquid chroma...
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ژورنال
عنوان ژورنال: Scientia Pharmaceutica
سال: 2011
ISSN: 0036-8709,2218-0532
DOI: 10.3797/scipharm.1012-03